Both MC 1 and MC 3 Receptors Provide Protection From Cerebral Ischemia-Reperfusion–Induced Neutrophil Recruitment
نویسندگان
چکیده
منابع مشابه
Both MC1 and MC3 Receptors Provide Protection From Cerebral Ischemia-Reperfusion-Induced Neutrophil Recruitment.
OBJECTIVE Neutrophil recruitment is a key process in the pathogenesis of stroke, and may provide a valuable therapeutic target. Targeting the melanocortin (MC) receptors has previously shown to inhibit leukocyte recruitment in peripheral inflammation, however, it is not known whether treatments are effective in the unique cerebral microvascular environment. Here, we provide novel research highl...
متن کاملThe MC @ NLO 3 . 1 Event Generator ∗
This is the user’s manual of MC@NLO 3.1. This package is a practical implementation, based upon the HERWIG event generator, of the MC@NLO formalism, which allows one to incorporate NLO QCD matrix elements consistently into a parton shower framework. Processes available in this version include the hadroproduction of single vector and Higgs bosons, vector boson pairs, heavy quark pairs, lepton pa...
متن کاملActivation of cannabinoid 2 receptors protects against cerebral ischemia by inhibiting neutrophil recruitment.
Activation of the cannabinoid 2 receptor (CB(2)) reduces ischemic injury in several organs. However, the mechanisms underlying this protective action are unclear. In a mouse model of ischemic stroke, we show that the CB(2) agonist JWH-133 (1 mg . kg(-1) . d(-1)) decreases the infarct size measured 3 d after onset of ischemia. The neuroprotective effect of JWH-133 was lost in CB(2)-deficient mic...
متن کاملThe MC @ NLO 3 . 4 Event Generator ∗
This is the user’s manual of MC@NLO 3.4. This package is a practical implementation, based upon the HERWIG event generator, of the MC@NLO formalism, which allows one to incorporate NLO QCD matrix elements consistently into a parton shower framework. Processes available in this version include the hadroproduction of single vector and Higgs bosons, vector boson pairs, heavy quark pairs, single to...
متن کاملThe MC @ NLO 2 . 3 Event Generator ∗
This is the user’s manual of MC@NLO 2.3. This package is a practical implementation, based upon the HERWIG event generator, of the MC@NLO formalism, which allows one to incorporate NLO QCD matrix elements consistently into a parton shower framework. Processes available in this version include the hadroproduction of single vector and Higgs bosons, vector boson pairs, heavy quark pairs, and lepto...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2015
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.115.305348